Sunday, November 7, 2010

Insuline Resistance and PCOS- what you need to know

Insulin Resistance, has many factors that contribute to its presence in the body.

 Some people may also have a genetic predisposition to Insulin Resistance, while others develop the condition through high stress and unhealthy lifestyles.  Clinicians now think that insulin resistance is a primary cause or trigger of PCOS.



Insulin Resistance reduces the insulin sensitivity of you cell walls. Glucose has to pass through those cell walls to be converted into energy. Insulin assists this process. But when the cells wall have become de-sensitized to insulin by Insulin resistance, the process can break down.


Glucose "bounces" off the cell wall, instead of passing through the insulin door to be burned as energy. With the cell door almost closed to it, glucose remains in the blood stream, causing elevated levels of blood sugar, which are sent to the liver. Once there, the sugar is converted into fat and stored via the blood stream throughout the body. This process can lead to weight gain and obesity, key factors in creating Polycystic Ovarian Syndrome.

The second way that Insulin Resistance causes PCOS is by raising insulin levels in the blood stream. Unhealthy lifestyles and genetic conditions cause the pancreas to overproduce insulin. The de-sensitized cell is, in turn, overwhelmed by this excess insulin and an excess of insulin "rejected" by the cell then free-floats in the blood stream, creating unbalanced hormone levels in PCOS sufferers.

Excess insulin stimulates the ovaries to produce large amounts of the male hormone testosterone, which may prevent the ovaries from releasing an egg each month, thus causing infertility. High levels of insulin also increase the conversion of androgens (male hormones) to estrogens (female hormones), upsetting a delicate balance between the two and having a direct effect on weight gain and the formation of cystic follicles or cysts in the ovary.

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